Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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VC_2532Conserved hypothetical protein; Displays ATPase and GTPase activities. (286 aa)    
Predicted Functional Partners:
VC_2531
PTS system, nitrogen regulatory IIA component; Similar to PID:2317740; identified by sequence similarity; putative.
  
  
 0.969
VC_2530
Sigma-54 modulation protein, putative; Similar to PID:2317739; identified by sequence similarity; putative.
 
  
 0.941
npr
Phosphocarrier protein NPr; Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein NPr by enzyme I-Ntr. Phospho-NPr then transfers it to EIIA-Ntr. Could function in the transcriptional regulation of sigma-54 dependent operons in conjunction with the NPr (PtsO) and EIIA-Ntr (PtsN) proteins; Belongs to the HPr family.
  
  
 0.911
VC_1023
Conserved hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
  
  
 0.862
VC_0419
Cytoplasmic axial filament protein; Similar to SP:P25537 PID:48826 PID:606187 GB:U00096 PID:1789645; identified by sequence similarity; putative.
 
 
 
 0.841
VC_2529
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.841
rne
Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.
   
 
 0.818
lptA
Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
  
    0.783
VC_2528
ABC transporter, ATP-binding protein; Similar to PID:2317737; identified by sequence similarity; putative.
  
  
 0.748
VC_2523
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.739
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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