STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_2536Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0307 family. (193 aa)    
Predicted Functional Partners:
rluD
Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family.
    
 
 0.842
rpmG
Ribosomal protein L33; Similar to GB:J01677 SP:P02436 PID:147709 PID:290486 GB:U00096; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL33 family.
    
   0.838
rpmF
Ribosomal protein L32; Similar to GB:L42023 SP:P44368 PID:1003217 PID:1222072 PID:1204415; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL32 family.
  
   0.788
cgtA
GTP1/Obg family protein; Depletion experiments lead to gene down regulation and a dramatic increase in ppGpp levels, like those seen in the stringent response. There is no change in cell morphology in depletion experiments , but cells are very sensitive to the DNA-damaging agent hydroxyurea and are very elongated. Overexpression reduces growth and leads to elongated cells. Overexpression of proteins with C-terminal deletions of 29 or 62 amino acids showed fewer elongated cells. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
    
 
 0.759
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.755
VC_2535
pmbA protein; Similar to SP:P24231 GB:X54152 PID:42440 PID:537077 GB:U00096; identified by sequence similarity; putative.
  
    0.753
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
    
 
 0.751
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.750
rpmH
Ribosomal protein L34; Similar to GB:L42023 SP:P44370 PID:1006197 PID:1221112 PID:1205248; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL34 family.
    
   0.745
rpmB
Ribosomal protein L28; Similar to GB:L42023 SP:P44364 PID:1006103 PID:1221060 PID:1205200; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL28 family.
    
   0.745
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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