Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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kefBGlutathione-regulated potassium-efflux system protein KefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (656 aa)    
Predicted Functional Partners:
kefG
NAD(P)H oxidoreductase, putative; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.
 
 
 0.995
VC_2605
Hypothetical protein; Identified by Glimmer2; putative.
       0.849
VC_2195
Flagellar basal-body rod protein FlgG; Similar to GB:U00096 SP:P75939 PID:1787318; identified by sequence similarity; putative; Belongs to the flagella basal body rod proteins family.
    
   0.822
VC_0992
Glutathione-regulated potassium-efflux system protein KefB, putative; Similar to SP:P52068 GB:U00096 PID:1773160 PID:1786685; identified by sequence similarity; putative; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
0.807
nhaP2
Conserved hypothetical protein; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
     
 0.765
nhaA
Na+/H+ antiporter protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Contributes to the survival of V.cholerae during the stationary and exponential growth phases in a saline environment.
 
   
 0.764
VC_2608
ABC transporter, ATP-binding protein; Similar to SP:P45535 PID:606286 GB:U00096 PID:1789751; identified by sequence similarity; putative.
     
 0.761
VC_2609
Hypothetical protein; Identified by Glimmer2; putative.
       0.755
VC_2610
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.755
VC_A0530
Pyruvate-flavoredoxin oxidoreductase; Similar to GB:U00096 PID:1742250 PID:1742256 PID:1787642; identified by sequence similarity; putative.
     
 0.754
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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