Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_2610Conserved hypothetical protein; Identified by Glimmer2; putative. (329 aa)    
Predicted Functional Partners:
VC_2608
ABC transporter, ATP-binding protein; Similar to SP:P45535 PID:606286 GB:U00096 PID:1789751; identified by sequence similarity; putative.
  
    0.851
VC_2609
Hypothetical protein; Identified by Glimmer2; putative.
       0.849
VC_2605
Hypothetical protein; Identified by Glimmer2; putative.
       0.755
kefB
Glutathione-regulated potassium-efflux system protein KefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
       0.755
kefG
NAD(P)H oxidoreductase, putative; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.
       0.755
VC_2612
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0270 family.
       0.726
slyD
Peptidyl-prolyl cis-trans isomerase, FKBP-type; Folding helper with both chaperone and peptidyl-prolyl cis- trans isomerase (PPIase) activities. Chaperone activity prevents aggregation of unfolded or partially folded proteins and promotes their correct folding. PPIases catalyze the cis-trans isomerization of Xaa- Pro bonds of peptides, which accelerates slow steps of protein folding and thus shortens the lifetime of intermediates. Both strategies lower the concentration of intermediates and increase the productivity and yield of the folding reaction; Belongs to the FKBP-type PPIase family.
       0.681
VC_2613
Phosphoribulokinase; Similar to SP:P37307 PID:606289 GB:U00096 PID:2367214; identified by sequence similarity; putative.
       0.656
VC_2603
Asparaginase, putative; Similar to SP:P37595 GB:U00096 PID:1787050; identified by sequence similarity; putative.
       0.573
VC_2614
Cyclic AMP receptor protein; Similar to GP:2580527; identified by sequence similarity; putative.
     
 0.515
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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