Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_2621Extracellular nuclease-related protein; Similar to PID:1185049; identified by sequence similarity; putative. (869 aa)    
Predicted Functional Partners:
dns
Extracellular deoxyribonuclease; Similar to GB:M16499 SP:P08038 PID:155163; identified by sequence similarity; putative.
     
 0.581
VC_2622
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.532
VC_1981
Hypothetical protein; Identified by Glimmer2; putative.
  
   
 0.529
VC_0904
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.507
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.501
epsN
General secretion pathway protein N; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity). Required for secretion of cholera toxin through the outer membrane.
  
     0.477
VC_1874
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
    0.475
VC_1686
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.458
VC_A0545
5`-nucleotidase, putative; Similar to GB:AE000520; identified by sequence similarity; putative; Belongs to the 5'-nucleotidase family.
 
   
 0.458
prtV
Protease; Metalloprotease that exhibits a cytotoxic effect leading to cell death. In host tissues, it could play a role in pathogenesis by modulating the stability of the extracellular matrix components such as fibronectin and fibrinogen. Also able to cleave plasminogen.
 
     0.452
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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