STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (346 aa)    
Predicted Functional Partners:
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 0.999
argD
Acetylornithine aminotransferase; Similar to GB:M32796 SP:P18335 PID:145337 PID:606293 GB:U00096; identified by sequence similarity; putative; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
 
 0.997
argA
N-acetylglutamate synthase; Similar to SP:P08205 GB:Y00492 PID:581038 PID:882710 GB:U00096; identified by sequence similarity; putative.
 
 
 0.996
argG
Argininosuccinate synthase; Similar to GB:AL009126; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
  
 0.995
argH
Argininosuccinate lyase; Similar to SP:P11447 GB:J01590 GB:M21446 PID:145335 PID:396307; identified by sequence similarity; putative.
 
  
 0.992
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
  
 0.974
argE
Acetylornithine deacetylase; Similar to SP:P23908 GB:X55417 GB:X62807 PID:396304 PID:40955; identified by sequence similarity; putative; Belongs to the peptidase M20A family. ArgE subfamily.
 
 
 0.973
argR
Arginine repressor; Regulates arginine biosynthesis genes.
 
  
 0.824
VC_2684
Aspartokinase II/homoserine dehydrogenase, methionine-sensitive; Similar to GB:L19201 SP:P00562 GB:J01651 GB:V00305 PID:146841; identified by sequence similarity; putative; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
  
 0.764
hisI
phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; Similar to SP:P06989 GB:D43637 GB:U02072 GB:X03974 PID:41700; identified by sequence similarity; putative; In the C-terminal section; belongs to the PRA-PH family.
 
  
 0.740
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.