STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
epmAlysyl-tRNA synthetase-related protein; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily. (349 aa)    
Predicted Functional Partners:
efp
Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.
 
 
 
 0.966
VC_2661
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.890
VC_1209
Elongation factor P family protein; Similar to SP:P33028 GB:D21148 PID:405887 PID:471105 GB:U00096; identified by sequence similarity; putative; Belongs to the elongation factor P family.
 
 
 
 0.868
VC_2654
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.726
frdC
Fumarate reductase, 15 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
     
 0.720
VC_2656
Fumarate reductase, flavoprotein subunit; Similar to GB:U14003 SP:P00363 GB:J01611 PID:145263 PID:536998; identified by sequence similarity; putative.
       0.713
VC_2657
Fumarate reductase, iron-sulfur protein; Similar to GB:U14003 SP:P00364 GB:J01611 PID:145264 PID:536997; identified by sequence similarity; putative; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
       0.713
frdD
Fumarate reductase, 13 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
       0.713
secB
Protein-transport protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
       0.636
VC_2113
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
   
 0.477
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.