| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| VC_0736 | rraA | VC_0736 | VC_2672 | Isocitrate lyase; Similar to SP:P05313 GB:M20714 GB:M22621 GB:X07543 GB:X12431; identified by sequence similarity; putative. | S-adenosylmethionine:2-demethylmenaquinone methyltransferase; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.539 |
| VC_1407 | rhlE | VC_1407 | VC_A0204 | ATP-dependent RNA helicase RhlE; Similar to GP:3288677; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. | ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. | 0.904 |
| VC_1407 | rne | VC_1407 | VC_2030 | ATP-dependent RNA helicase RhlE; Similar to GP:3288677; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.638 |
| VC_1407 | rraA | VC_1407 | VC_2672 | ATP-dependent RNA helicase RhlE; Similar to GP:3288677; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. | S-adenosylmethionine:2-demethylmenaquinone methyltransferase; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.525 |
| VC_2564 | rne | VC_2564 | VC_2030 | ATP-dependent RNA helicase DbpA; Similar to SP:P21693 GB:X52647 PID:41248 GB:U00096 PID:1742212; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.638 |
| VC_2564 | rraA | VC_2564 | VC_2672 | ATP-dependent RNA helicase DbpA; Similar to SP:P21693 GB:X52647 PID:41248 GB:U00096 PID:1742212; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. | S-adenosylmethionine:2-demethylmenaquinone methyltransferase; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.525 |
| hslU | menA | VC_2674 | VC_2673 | Protease HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.738 |
| hslU | rraA | VC_2674 | VC_2672 | Protease HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | S-adenosylmethionine:2-demethylmenaquinone methyltransferase; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.685 |
| menA | hslU | VC_2673 | VC_2674 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Protease HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.738 |
| menA | rraA | VC_2673 | VC_2672 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | S-adenosylmethionine:2-demethylmenaquinone methyltransferase; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.873 |
| rhlB | rne | VC_0305 | VC_2030 | ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.775 |
| rhlB | rraA | VC_0305 | VC_2672 | ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | S-adenosylmethionine:2-demethylmenaquinone methyltransferase; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.638 |
| rhlE | VC_1407 | VC_A0204 | VC_1407 | ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. | ATP-dependent RNA helicase RhlE; Similar to GP:3288677; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. | 0.904 |
| rhlE | rne | VC_A0204 | VC_2030 | ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.710 |
| rhlE | rraA | VC_A0204 | VC_2672 | ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. | S-adenosylmethionine:2-demethylmenaquinone methyltransferase; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.597 |
| rne | VC_1407 | VC_2030 | VC_1407 | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | ATP-dependent RNA helicase RhlE; Similar to GP:3288677; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. | 0.638 |
| rne | VC_2564 | VC_2030 | VC_2564 | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | ATP-dependent RNA helicase DbpA; Similar to SP:P21693 GB:X52647 PID:41248 GB:U00096 PID:1742212; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. | 0.638 |
| rne | rhlB | VC_2030 | VC_0305 | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.775 |
| rne | rhlE | VC_2030 | VC_A0204 | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. | 0.710 |
| rne | rraA | VC_2030 | VC_2672 | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | S-adenosylmethionine:2-demethylmenaquinone methyltransferase; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. | 0.709 |
