Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_2696fxsA protein; Similar to GB:U14003 SP:P37147 GB:X04066 PID:41007 PID:536984; identified by sequence similarity; putative. (161 aa)    
Predicted Functional Partners:
hslV
Protease HslVU, subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
    0.814
VC_0977
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
    0.811
VC_2698
Aspartate ammonia-lyase; Similar to GB:L42023 SP:P44324 PID:1003952 PID:1222469 PID:1204785; identified by sequence similarity; putative.
       0.646
htpX
Heat shock protein HtpX; Similar to GB:M58470 SP:P23894 PID:146412 GB:U00096 PID:1736470; identified by sequence similarity; putative; Belongs to the peptidase M48B family.
   
  
 0.619
hslU
Protease HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
   
    0.616
VC_1033
Cation transport ATPase, E1-E2 family; Similar to SP:P37617 PID:466605 GB:U00096 PID:1789879; identified by sequence similarity; putative.
      
 0.580
VC_0608
iron(III) ABC transporter, periplasmic iron-compound-binding protein; Similar to PID:1651916; identified by sequence similarity; putative.
      
 0.567
VC_2045
Superoxide dismutase, Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
     
 0.552
VC_0018
16 kDa heat shock protein A; Similar to GB:L10328 SP:P29209 GB:M94104 PID:147369 PID:290536; identified by sequence similarity; putative; Belongs to the small heat shock protein (HSP20) family.
   
    0.551
VC_2697
GGDEF family protein; Similar to PID:576655 PID:576657; identified by sequence similarity; putative.
       0.539
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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