Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
VC_2698Aspartate ammonia-lyase; Similar to GB:L42023 SP:P44324 PID:1003952 PID:1222469 PID:1204785; identified by sequence similarity; putative. (483 aa)    
Predicted Functional Partners:
VC_1995
Similar to SP:P18840 PID:145279 GB:U00096 PID:1742878 PID:1788065; identified by sequence similarity; putative.
  
 
 0.969
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
  
 
 0.943
argH
Argininosuccinate lyase; Similar to SP:P11447 GB:J01590 GB:M21446 PID:145335 PID:396307; identified by sequence similarity; putative.
     
0.913
VC_1126
Adenylosuccinate lyase; Similar to GB:M74924 SP:P25739 PID:145203 PID:42585 GB:U00096; identified by sequence similarity; putative; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.908
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.908
VC_2603
Asparaginase, putative; Similar to SP:P37595 GB:U00096 PID:1787050; identified by sequence similarity; putative.
    
 0.904
VC_0991
Asparagine synthetase B, glutamine-hydrolyzing; Similar to GB:J05554 SP:P22106 PID:145393 GB:U00096 PID:1651277; identified by sequence similarity; putative.
     
 0.903
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.903
pyrB
Aspartate carbamoyltransferase, catalytic subunit; Similar to PID:1708787; identified by sequence similarity; putative.
     
  0.900
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
     
  0.900
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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