Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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nhaP2Conserved hypothetical protein; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily. (581 aa)    
Predicted Functional Partners:
kefB
Glutathione-regulated potassium-efflux system protein KefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
     
 0.765
nhaA
Na+/H+ antiporter protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Contributes to the survival of V.cholerae during the stationary and exponential growth phases in a saline environment.
     
 0.577
VC_A0157
NADH dehydrogenase, putative; Similar to GB:AL009126; identified by sequence similarity; putative.
      
 0.552
nhaB
Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
      
 0.514
opgG
Periplasmic glucans biosynthesis protein MdoG; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
  
  
 0.464
VC_0043
Potassium uptake protein TrkA; Similar to GB:D28477 SP:P39448 PID:541661; identified by sequence similarity; putative.
     
 0.457
VC_0689
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
   
0.456
rnfA
RnfA-related protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
      
 0.426
VC_A0154
Conserved hypothetical protein; Identified by Glimmer2; putative.
      
 0.426
opgH
Periplasmic glucans biosynthesis protein MdoH; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
  
   
 0.422
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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