STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysQcysQ protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (301 aa)    
Predicted Functional Partners:
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
 
 
 0.905
VC_2721
MutT/nudix family protein; Similar to SP:P45799 PID:606331 GB:U00096 PID:1789800; identified by sequence similarity; putative; Belongs to the Nudix hydrolase family.
  
    0.838
VC_0745
Inositol monophosphate family protein; Similar to GB:M34828 SP:P22783 PID:147899 GB:U00096 PID:1788882; identified by sequence similarity; putative; Belongs to the inositol monophosphatase superfamily.
 
  
0.823
cysD
Sulfate adenylate transferase, subunit 2; Similar to GB:M74586 SP:P21156 PID:145669 PID:145672 PID:882645; identified by sequence similarity; putative.
 
 
 0.820
cysN
Sulfate adenylate transferase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
 
 0.768
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
  
 
 0.751
nfuA
Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
       0.651
VC_0426
Hypothetical protein; Identified by Glimmer2; putative.
    
  0.649
VC_A0593
Hypothetical protein; Identified by Glimmer2; putative.
     
 0.641
VC_1516
Iron-sulfur cluster-binding protein; Similar to GB:X61204 PID:44800 PID:1747410; identified by sequence similarity; putative.
    
 0.626
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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