STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_2742Ribonuclease BN; Similar to GB:L19201 SP:P32146 PID:304990 GB:U00096 PID:1790319; identified by sequence similarity; putative. (297 aa)    
Predicted Functional Partners:
dtd
Conserved hypothetical protein; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
       0.831
VC_2743
Hypothetical protein; Identified by Glimmer2; putative.
       0.785
VC_2740
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.751
VC_2744
GTP-binding protein TypA; Similar to GB:L19201 SP:P32132 PID:304976 GB:U00096 PID:1790302; identified by sequence similarity; putative.
       0.728
guaB
Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.499
VC_2745
Hypothetical protein; Identified by Glimmer2; putative.
       0.471
VC_A0930
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
    0.452
VC_0916
Phosphotyrosine protein phosphatase; Similar to SP:P41893 PID:602992; identified by sequence similarity; putative; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
  
 0.448
VC_1041
Phosphotyrosine protein phosphatase; Similar to PID:1001414 PID:1001408; identified by sequence similarity; putative; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
  
 0.448
hemL
Glutamate-1-semialdehyde 2,1-aminomutase; Similar to GB:D26562 SP:P23893 GB:X53696 PID:41621 PID:473813; identified by sequence similarity; putative.
      
 0.426
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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