STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addAdenosine deaminase; Similar to GB:M59033 SP:P22333 PID:145201 GB:U00096 PID:1742677; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (334 aa)    
Predicted Functional Partners:
VC_1129
Inosine-guanosine kinase; Similar to GB:D00798 SP:P22937 PID:216562 PID:520811 PID:216519; identified by sequence similarity; putative.
  
 
 0.937
VC_A0801
Inosine-guanosine kinase; Similar to GB:D00798 SP:P22937 PID:216562 PID:520811 PID:216519; identified by sequence similarity; putative.
  
 
 0.936
deoD1
Purine nucleoside phosphorylase; Similar to PID:1732037; identified by sequence similarity; putative.
    
 0.915
deoD2
Purine nucleoside phosphorylase; Similar to GB:U14003 SP:P09743 GB:M60917 PID:147309 PID:537224; identified by sequence similarity; putative.
    
 0.915
surE
Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.907
nutA
UDP-sugar hydrolase; Degradation of extracellular 5'-nucleotides for nutritional needs.
    
 0.906
VC_2416
2`,3`-cyclic-nucleotide 2`-phosphodiesterase, putative; Similar to GB:AE000511 PID:2313187; identified by sequence similarity; putative; Belongs to the 5'-nucleotidase family.
    
 0.906
VC_2562
2`,3`-cyclic-nucleotide 2`-phosphodiesterase; Similar to SP:P08331 GB:M13464 PID:145584 GB:U00096 PID:1790658; identified by sequence similarity; putative; Belongs to the 5'-nucleotidase family.
    
 0.906
VC_A0545
5`-nucleotidase, putative; Similar to GB:AE000520; identified by sequence similarity; putative; Belongs to the 5'-nucleotidase family.
    
 0.906
ppnP
Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
 0.905
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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