STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_2760Transcriptional regulator, LysR family; Similar to SP:P37598 GB:U00096 PID:1742732 PID:1742742 PID:1787949; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family. (302 aa)    
Predicted Functional Partners:
VC_2761
Multidrug resistance protein; Similar to GB:U00096 PID:1742733 PID:1742743 PID:1787950; identified by sequence similarity; putative.
 
     0.808
VC_A0082
Transcriptional regulator, LysR family; Similar to PID:1652750; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.691
VC_1049
Transcriptional regulator, LysR family; Similar to GP:1139588; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.653
VC_1955
Transcriptional regulator, LysR family; Similar to PID:1652912; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.653
VC_A0635
Transcriptional regulator, LysR family; Similar to GB:U00096 PID:1788100; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.653
VC_A0833
Transcriptional regulator, LysR family; Similar to GB:AE000657; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.635
irgB
Iron-regulated virulence regulatory protein IrgB; Transcription activation of the irgA gene. In the presence of sufficient iron, transcription of both irgA and irgB is negatively regulated by a fur-like protein. In low iron conditions, negative regulation of transcription is removed, and production of irgB leads to positive transcriptional activation of irgA (By similarity).
  
     0.631
VC_A0991
Transcriptional regulator, LysR family; Similar to PID:1652912; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.623
VC_A0889
Transcriptional regulator, LysR family; Similar to PID:924993 SP:P52689; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.596
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.542
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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