Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
malTmalT regulatory protein; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box. (921 aa)    
Predicted Functional Partners:
alaE
Conserved hypothetical protein; Exports L-alanine; Belongs to the AlaE exporter family.
  
     0.726
VC_0018
16 kDa heat shock protein A; Similar to GB:L10328 SP:P29209 GB:M94104 PID:147369 PID:290536; identified by sequence similarity; putative; Belongs to the small heat shock protein (HSP20) family.
    
 
 0.722
lamB
Maltoporin; Involved in the transport of maltose and maltodextrins; Belongs to the porin LamB (TC 1.B.3) family.
 
   
 0.679
VC_A0945
Maltose ABC transporter, periplasmic maltose-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.
 
     0.659
VC_A1027
Maltose operon periplasmic protein, putative; Similar to SP:P03841 GB:J01648 GB:M26131 GB:X04477 PID:146595; identified by sequence similarity; putative.
 
     0.659
VC_A0860
Alpha-amylase; Similar to SP:P25718 GB:X58994 PID:41966 PID:466709 GB:U00096; identified by sequence similarity; putative.
 
     0.646
VC_0144
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.644
VC_A1103
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.618
dnaJ
dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]
    
 
 0.591
acfD
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.552
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.