Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0022Glutathione S-transfersae-related protein; Similar to GB:U77604 PID:1747521; identified by sequence similarity; putative. (133 aa)    
Predicted Functional Partners:
vasW
Hypothetical protein; Plays an accessory role in VasX-mediated bacterial killing.
       0.530
vasX
Hypothetical protein; Toxin secreted by the type VI (T6SS) secretion system that acts on prokaryotic target cells. Acts in conjunction with VasW, an accessory protein to VasX, to compromise the inner membrane of prokaryotic target cells.
       0.523
tsiV2
Hypothetical protein; Immunity protein that plays a role in preventing early activation of toxin VasX.
       0.523
vgrG2
vgrG protein; Part of the type VI secretion system specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection. Forms the spike at the tip of the elongating tube formed by haemolysin co- regulated protein Hcp. Allows the delivery of the VasX antibacterial toxin to target cells where it exerts its toxicity.
       0.522
VC_1871
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0304 family.
  
     0.468
VC_1857
Primosomal replication protein N``; Similar to GB:D13958 PID:912452 GB:U00096 PID:1773149 PID:1786673; identified by sequence similarity; putative.
  
     0.450
VC_A0017
Hcp protein; Similar to GP:1488371; identified by sequence similarity; putative.
 
     0.434
VC_1841
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.422
VC_2112
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.409
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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