STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0034Conserved hypothetical protein; Identified by Glimmer2; putative. (290 aa)    
Predicted Functional Partners:
flgI
Flagellar P-ring protein FlgI; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
     0.627
VC_2195
Flagellar basal-body rod protein FlgG; Similar to GB:U00096 SP:P75939 PID:1787318; identified by sequence similarity; putative; Belongs to the flagella basal body rod proteins family.
 
    0.579
VC_A0447
Haemagglutinin associated protein; Similar to GB:X64387 PID:396849 PID:48357; identified by sequence similarity; putative; Belongs to the N(4)/N(6)-methyltransferase family.
      
 0.574
VC_2126
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
    0.564
VC_A0035
Phosphatidylglycerophosphatase B, putative; Similar to GB:M23628 SP:P18201 PID:450384 GB:U00096 PID:1742092; identified by sequence similarity; putative.
       0.539
fliG
Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
  
     0.500
flgH
Flagellar L-ring protein FlgH; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
     0.500
VC_2198
Basal-body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
 
    0.498
VC_1348
Response regulator; Probable phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP). Increases motility and decreases biofilm formation in vivo.
 
     0.484
fliA
RNA polymerase sigma factor for flagellar operon FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
 
     0.473
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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