STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0035Phosphatidylglycerophosphatase B, putative; Similar to GB:M23628 SP:P18201 PID:450384 GB:U00096 PID:1742092; identified by sequence similarity; putative. (274 aa)    
Predicted Functional Partners:
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
 0.837
VC_1215
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Similar to GB:M12299 SP:P06978 PID:473749 GB:U00096 PID:1736571; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
 0.832
VC_1935
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase-related protein; Similar to GB:U00096 PID:1787676; identified by sequence similarity; putative.
  
 
 0.832
clsA
Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
    
 0.821
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
    
   0.796
VC_0249
rfbL protein; Similar to GB:X59554 PID:48391; identified by sequence similarity; putative.
    
 0.794
VC_1971
O-succinylbenzoic acid--CoA ligase; Similar to GB:L35031 SP:P37353 PID:520813 GB:U00096 PID:1788595; identified by sequence similarity; putative.
    
 0.794
VC_1985
long-chain-fatty-acid--CoA ligase; Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096; identified by sequence similarity; putative.
    
 0.794
VC_1534
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
 0.776
mukB
Cell division protein MukB; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.
  
     0.739
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.