STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gltSSodium/glutamate symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family. (408 aa)    
Predicted Functional Partners:
VC_2323
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
    0.712
VC_A0524
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
    0.688
VC_1168
Proton/glutamate symporter; Similar to SP:P21345 GB:M32488 GB:M84805 PID:147160 PID:396412; identified by sequence similarity; putative; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
     
 0.544
VC_A0088
Proton/glutamate symporter; Similar to SP:P21345 GB:M32488 GB:M84805 PID:147160 PID:396412; identified by sequence similarity; putative; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
     
 0.544
VC_0330
Regulator of sigma D; Similar to SP:P31690 PID:396334 GB:U00096 PID:1790428; identified by sequence similarity; putative; Belongs to the Rsd/AlgQ family.
      
 0.458
VC_1773
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.439
kup
Potassium uptake protein, Kup system; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.
      
 0.433
VC_1005
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.420
nanM
Conserved hypothetical protein; Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta- anomer, accelerating the equilibrium between the alpha- and beta- anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses; Belongs to the NanM family.
  
     0.420
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.