Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0043Conserved hypothetical protein; Identified by Glimmer2; putative. (94 aa)    
Predicted Functional Partners:
rpiA
Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
    0.670
VC_A0042
Hypothetical protein; May act as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Increasing levels of c-di-GMP lead to decreased motility (Potential). Binds bis-(3'-5') cyclic diguanylic acid (c-di-GMP) with a dissociation constant of 170 nM in the presence of 10 mM KCl and with 100 nM in its absence. Binds 1 to 2 c-di-GMP per subunit. Only 1 c-di- GMP is seen in the wild-type crystal, while 2 are seen in the mutant. Depending on the concentration of K(+) stoichiometries of 1:1, 1.43:1 and 2:1 are determined by is [...]
       0.608
VC_A0864
Methyl-accepting chemotaxis protein; Similar to GB:L29189 SP:P39214 PID:459690 GB:AL009126; identified by sequence similarity; putative.
      
 0.604
VC_A0075
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.579
rbsD
Ribose ABC transporter protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
      
 0.441
VC_A0044
Hypothetical protein; Identified by Glimmer2; putative.
       0.429
VC_A0045
Protease-related protein; Similar to PID:1707703; identified by sequence similarity; putative.
       0.429
VC_A0565
Sensor histidine kinase; Similar to GB:AE000511 PID:2313251; identified by sequence similarity; putative.
      
 0.415
VC_0916
Phosphotyrosine protein phosphatase; Similar to SP:P41893 PID:602992; identified by sequence similarity; putative; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
   
  
 0.400
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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