Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0055Conserved hypothetical protein; Identified by Glimmer2; putative. (322 aa)    
Predicted Functional Partners:
phrA
Deoxyribodipyrimidine photolyase; Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.
  
  
 0.958
VC_A0056
Transcriptional regulator, MerR family; Similar to SP:P33358 PID:405858 GB:U00096 PID:1788448; identified by sequence similarity; putative.
  
  
 0.929
cry2
Deoxyribodipyrimidine photolyase, putative; Has no photolyase activity.
  
  
 0.857
cry1
Deoxyribodipyrimidine photolyase; May have a photoreceptor function. Binds DNA; probably functions as a transcriptional repressor (By similarity). Has no photolyase activity. Upon purification from either V.cholerae or E.coli an approximately 60 nucleotide RNA is associated with the protein.
  
  
 0.856
VC_A0058
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.842
VC_A0052
Hypothetical protein; Identified by Glimmer2; putative.
       0.703
thiI
Thiamin biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
   
 0.683
VC_1118
Transcriptional regulator, putative; Similar to PID:1653608; identified by sequence similarity; putative.
  
  
 0.599
VC_1122
Cyclopropane-fatty-acyl-phospholipid synthase; Similar to GB:M98330 SP:P30010 PID:145514 GB:U00096 PID:1742735; identified by sequence similarity; putative.
  
  
 0.568
VC_2303
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.563
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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