Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0063Protease II; Similar to GB:D10976 SP:P24555 PID:216624 GB:U00096 PID:1736485; identified by sequence similarity; putative. (665 aa)    
Predicted Functional Partners:
VC_A0064
TonB system receptor, putative; Similar to GB:L27149 PID:529727; identified by sequence similarity; putative.
 
     0.837
VC_A0066
Hypothetical protein; Identified by Glimmer2; putative.
       0.781
VC_A0065
Hypothetical protein; Identified by Glimmer2; putative.
       0.774
VC_A0067
Hypothetical protein; Identified by Glimmer2; putative.
       0.762
VC_0565
Protease DegS; Similar to SP:P31137 GB:U15661 GB:U00096 PID:1789630; identified by sequence similarity; putative.
   
  
 0.564
VC_A0062
Hypothetical protein; Identified by Glimmer2; putative.
       0.543
clpP
ATP-dependent Clp protease, proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.499
VC_0001
Hypothetical protein; Identified by Glimmer2; putative.
   
  
 0.478
VC_1055
Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.460
VC_2072
Peptidase, insulinase family; Similar to SP:P35559 PID:56492; identified by sequence similarity; putative; Belongs to the peptidase M16 family.
      
 0.400
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (8%) [HD]