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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (306 aa)    
Predicted Functional Partners:
rbsD
Ribose ABC transporter protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
 
  
 0.961
VC_A0130
Ribose ABC transporter, periplasmic D-ribose-binding protein; Similar to GB:L42023 SP:P44737 PID:1003892 PID:1222436 PID:1204755; identified by sequence similarity; putative.
 
  
 0.912
VC_A0132
Ribose operon repressor; Similar to GB:L10328 SP:P25551 GB:D10466 GB:M13169 PID:147517; identified by sequence similarity; putative.
 
 0.899
VC_A0129
Ribose ABC transporter, permease protein; Similar to GB:L10328 SP:P04984 GB:M13169 PID:147514 PID:290600; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.896
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.888
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.844
rpiA
Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
 0.844
VC_1822
PTS system, fructose-specific IIABC component; Similar to GB:AL009126; identified by sequence similarity; putative.
    
 0.841
VC_1826
PTS system, fructose-specific IIABC component; Similar to GB:AL009126; identified by sequence similarity; putative.
    
 0.841
rfbA
Mannose-1-phosphate guanylyltransferase; Similar to GB:X59554 SP:Q07024 PID:48383; identified by sequence similarity; putative.
    
 0.814
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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