STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0140Spindolin-related protein; Similar to PID:1145625; identified by sequence similarity; putative. (402 aa)    
Predicted Functional Partners:
VC_A0700
Chitodextrinase; Similar to GP:3928775; identified by sequence similarity; putative.
 
 0.990
VC_1073
Chitinase, putative; Similar to PID:1698444; identified by sequence similarity; putative.
 
 
 0.984
VC_1952
Chitinase; Similar to GP:3851166; identified by sequence similarity; putative.
 
 
 0.968
VC_A0027
Chitinase; Similar to SP:P32823 PID:216207; identified by sequence similarity; putative.
 
0.963
VC_2217
beta-N-acetylhexosaminidase; Similar to PID:1698442; identified by sequence similarity; putative.
  
  
 0.931
VC_0613
beta-N-acetylhexosaminidase; Similar to PID:1698442; identified by sequence similarity; putative.
  
  
 0.908
gbpA
Chitinase, putative; Probably interacts with GlcNAc residues. May promote attachment to both epithelial cell surfaces and chitin. This function enhances bacterial colonization in the gastrointestinal tract and may also be important in the environment by augment colonization of chitinous structures, leading to improved survival. Promotes bacterial attachment to, and colonization of, zooplankton in the aquatic ecosystem; Belongs to the GbpA family.
 
  
 0.820
vcc
Collagenase; Possesses gelatinolytic activity; Belongs to the peptidase M9A family.
 
  
 0.801
nagZ
Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Plays a role in beta-lactam antibiotic resistance via its role in generating anhydro-N-acetylmuramic acid-linked peptides; these peptides function as signaling molecules that induce high-level expression of the beta-lactamase AmpC.
     
 0.797
hap
Hemagglutinin/protease; May play a role in the pathogenesis of cholera. Hap nicks and activates the A subunit of cholera enterotoxin and related enterotoxins.
  
  
 0.794
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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