Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0159Conserved hypothetical protein; Identified by Glimmer2; putative. (313 aa)    
Predicted Functional Partners:
VC_A0158
Hypothetical protein; Identified by Glimmer2; putative.
       0.591
VC_A0160
Tryptophan-specific transport protein; Similar to GB:L42023 SP:P44614 PID:1003469 PID:1222213 PID:1204542; identified by sequence similarity; putative.
 
     0.529
VC_A1017
methylated-DNA--protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.479
dksA
dnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.
 
  
 0.457
ompW
Outer membrane protein OmpW; Similar to SP:P17266 PID:48376 PID:2199526; identified by sequence similarity; putative.
  
  
 0.453
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
   
    0.450
VC_2502
DNA polymerase III, chi subunit; Similar to SP:P28905 SP:P11649 GB:L04574 GB:X15130 GB:Z14155; identified by sequence similarity; putative.
  
     0.447
VC_0076
Universal stress protein A; Similar to GB:U00039 SP:P28242 GB:X67639 PID:43280 PID:466632; identified by sequence similarity; putative.
   
  
 0.440
VC_0428
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
  
 0.440
pta
Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.419
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.