Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
VC_A0182Sigma-54 dependent transcriptional regulator; Similar to SP:P37013 GB:D28595 GB:U03846 PID:434587 PID:434588; identified by sequence similarity; putative. (530 aa)    
Predicted Functional Partners:
hmp
Ferrisiderophore reductase; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). Belongs to the globin family. Two-domain flavohemoproteins subfamily.
     
 0.871
VC_2529
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.824
VC_1349
Sensory box sensor histidine kinase/response regulator; Similar to PID:1653075; identified by sequence similarity; putative.
   
 
 0.779
VC_2369
Sensor histidine kinase FexB; Similar to SP:P22763 GB:X53315 PID:40951 PID:606149 GB:U00096; identified by sequence similarity; putative.
   
 
 0.779
VC_0303
Sensor histidine kinase; Similar to GP:2808665; identified by sequence similarity; putative.
   
 
 0.775
VC_1156
Sensor histidine kinase; Similar to GP:2655263; identified by sequence similarity; putative.
   
 
 0.752
VC_1157
Response regulator; Similar to PID:643672; identified by sequence similarity; putative.
   
 
 0.752
VC_2370
Sensory box/GGDEF family protein; Similar to PID:1652133; identified by sequence similarity; putative.
   
 
 0.721
VC_1315
Sensor histidine kinase; Similar to SP:P26489 GB:X56658 GB:X59071 PID:38703 PID:38705; identified by sequence similarity; putative.
 
 
 
 0.671
VC_1925
C4-dicarboxylate transport sensor protein; Similar to SP:P10047 GB:X06253 GB:Z11529 PID:46179 PID:46182; identified by sequence similarity; putative.
 
 
 
 0.643
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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