Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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nnrConserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity). In the N-terminal section; belongs to the NnrE/AIBP family. (494 aa)    
Predicted Functional Partners:
VC_0343
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
 
 0.880
VC_A0190
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.796
VC_A0189
Response regulator; Similar to PID:1736859 PID:1736868; identified by sequence similarity; putative.
       0.794
rppH
MutT/nudix family protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
  
 0.785
VC_1302
MutT/nudix family protein; Similar to SP:P43337 GB:U00096 PID:1788115; identified by sequence similarity; putative.
  
 0.785
VC_1342
MutT/nudix family protein; Similar to SP:P32091 PID:298045; identified by sequence similarity; putative.
  
 0.785
VC_2392
Mutator MutT protein; Similar to GB:D10483 SP:P08337 GB:M20791 GB:X04831 PID:147795; identified by sequence similarity; putative; Belongs to the Nudix hydrolase family.
  
 0.785
VC_2435
MutT/nudix family protein; Similar to SP:P36651 PID:882564 GB:U00096 PID:1789412; identified by sequence similarity; putative.
  
 0.785
VC_A0764
MutT/nudix family protein; Similar to SP:P54570 PID:1303984 GB:AL009126; identified by sequence similarity; putative.
  
 0.785
rhlB
ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.
   
 0.754
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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