Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0214Multidrug resistance protein D; Similar to GB:L10328 SP:P31442 PID:290522 GB:U00096 PID:1790107; identified by sequence similarity; putative. (414 aa)    
Predicted Functional Partners:
VC_A0215
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
gbpA
Chitinase, putative; Probably interacts with GlcNAc residues. May promote attachment to both epithelial cell surfaces and chitin. This function enhances bacterial colonization in the gastrointestinal tract and may also be important in the environment by augment colonization of chitinous structures, leading to improved survival. Promotes bacterial attachment to, and colonization of, zooplankton in the aquatic ecosystem; Belongs to the GbpA family.
  
   
 0.758
VC_A0140
Spindolin-related protein; Similar to PID:1145625; identified by sequence similarity; putative.
  
   
 0.606
VC_A0216
Hypothetical protein; Identified by Glimmer2; putative.
       0.559
VC_A0027
Chitinase; Similar to SP:P32823 PID:216207; identified by sequence similarity; putative.
  
   
 0.449
tolC
Outer membrane protein TolC; Outer membrane channel, which is required for the function of several efflux systems (By similarity). Required to export RtxA cytotoxin; Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
   
 
 0.412
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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