Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hlyCLactonizing lipase; Catalyzes the hydrolysis of triacylglycerol. Belongs to the AB hydrolase superfamily. Pseudomonas lipase family. (339 aa)    
Predicted Functional Partners:
lifO
Lipase activator protein, putative; May be involved in the folding of the extracellular lipase during its passage through the periplasm; Belongs to the lipase chaperone family.
 
 
 0.994
VC_A0714
Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
     
 0.902
VC_2341
long-chain-fatty-acid--CoA ligase, putative; Similar to GB:AE000782; identified by sequence similarity; putative.
  
 
 0.848
VC_2484
long-chain-fatty-acid--CoA ligase, putative; Similar to GB:L42023 SP:P44446 PID:1004105 PID:1221904 PID:1204261; identified by sequence similarity; putative.
   
 
 0.805
VC_1985
long-chain-fatty-acid--CoA ligase; Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096; identified by sequence similarity; putative.
     
 0.804
hlyB
Hemolysin secretion protein HylB; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.
     
 0.704
ubiB
Ubiquinone biosynthesis protein AarF, putative; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
   
   0.622
rplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
   0.615
rplL
Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
   
   0.612
cyaY
cyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
    
   0.607
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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