Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0238Sensor histidine kinase; Similar to PID:1064813 GB:AL009126; identified by sequence similarity; putative. (549 aa)    
Predicted Functional Partners:
VC_A0239
Transcriptional regulator; Similar to SP:Q44006; identified by sequence similarity; putative.
 
 
 0.971
VC_A0532
DNA-binding response regulator; Similar to GB:U00096 PID:1651301 PID:1786911; identified by sequence similarity; putative.
 
 
 0.863
VC_2692
Transcriptional regulator CpxR; Similar to GB:L19201 SP:P16244 GB:L14579 GB:X13307 PID:145589; identified by sequence similarity; putative.
 
 
 0.858
VC_A1105
DNA-binding response regulator; Similar to PID:882555 SP:P52076 GB:U00096 PID:1789402; identified by sequence similarity; putative.
 
 
 0.851
VC_1638
DNA-binding response regulator; Similar to PID:929822; identified by sequence similarity; putative.
 
 
 0.842
VC_1719
DNA-binding response regulator TorR; Similar to GB:X78195 SP:P38684 PID:1122858 GB:U00096 PID:1651487; identified by sequence similarity; putative.
 
 
 0.821
VC_0719
DNA-binding response regulator PhoB; Similar to GP:3282774; identified by sequence similarity; putative.
 
 
 0.815
VC_2368
Aerobic respiration control protein FexA; Similar to SP:P03026 GB:M10044 PID:145818 PID:537241 GB:U00096; identified by sequence similarity; putative.
 
 
 0.794
VC_2714
Transcriptional regulator OmpR; Similar to PID:2108342; identified by sequence similarity; putative.
 
 
 0.791
VC_A0256
Transcriptional regulator; Similar to GB:M31794 SP:P45605 PID:149295; identified by sequence similarity; putative.
 
 
 0.791
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.