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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0238Sensor histidine kinase; Similar to PID:1064813 GB:AL009126; identified by sequence similarity; putative. (549 aa)    
Predicted Functional Partners:
VC_A0239
Transcriptional regulator; Similar to SP:Q44006; identified by sequence similarity; putative.
 
 0.983
VC_1349
Sensory box sensor histidine kinase/response regulator; Similar to PID:1653075; identified by sequence similarity; putative.
 
 
0.957
VC_2369
Sensor histidine kinase FexB; Similar to SP:P22763 GB:X53315 PID:40951 PID:606149 GB:U00096; identified by sequence similarity; putative.
 
 
0.957
VC_0303
Sensor histidine kinase; Similar to GP:2808665; identified by sequence similarity; putative.
   
0.948
VC_0622
Sensory box sensor histidine kinase/response regulator; Similar to PID:939724; identified by sequence similarity; putative.
 
0.947
VC_1653
Sensory box sensor histidine kinase/response regulator VieS; Similar to GP:3123890; identified by sequence similarity; putative.
 
 
0.927
VC_A0532
DNA-binding response regulator; Similar to GB:U00096 PID:1651301 PID:1786911; identified by sequence similarity; putative.
 
 0.921
VC_2692
Transcriptional regulator CpxR; Similar to GB:L19201 SP:P16244 GB:L14579 GB:X13307 PID:145589; identified by sequence similarity; putative.
 
 0.918
VC_A1105
DNA-binding response regulator; Similar to PID:882555 SP:P52076 GB:U00096 PID:1789402; identified by sequence similarity; putative.
 
 0.914
VC_1638
DNA-binding response regulator; Similar to PID:929822; identified by sequence similarity; putative.
 
 0.909
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.