Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0245PTS system, IIA component; Similar to GB:U14003 SP:P39303 PID:537036 GB:U00096 PID:2367359; identified by sequence similarity; putative. (168 aa)    
Predicted Functional Partners:
VC_A0246
SgaT protein; Similar to GB:U14003 SP:P39301 PID:537034 GB:U00096 PID:2367358; identified by sequence similarity; putative.
 
 
 0.997
VC_A0248
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
 
 0.985
VC_A0242
Hexulose-6-phosphate synthase SgbH, putative; Similar to GB:L42023 SP:P44988 PID:1006248 PID:1221139 PID:1205273; identified by sequence similarity; putative.
 
  
 0.978
VC_A0241
Hexulose-6-phosphate isomerase SgbU, putative; Similar to GB:L42023 SP:P44990 PID:1006252 PID:1221141 PID:1205275; identified by sequence similarity; putative.
 
  
 0.963
VC_A0244
Sugar isomerase SgaE, AraD/FucA family; Similar to GB:L42023 SP:P44989 PID:1006250 PID:1221140 PID:1205274; identified by sequence similarity; putative.
 
  
 0.927
ptsH
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
  
 
 0.907
VC_A0243
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.870
VC_A0240
Hypothetical protein; Identified by Glimmer2; putative.
       0.845
mtlA
PTS system, mannitol-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in D-mannitol transport.
 
  
0.707
VC_1821
PTS system, fructose-specific IIBC component; Similar to SP:P32672 GB:U00006 PID:396296 GB:U00096 PID:1790386; identified by sequence similarity; putative.
 
  
 0.635
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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