Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0250Alpha-amylase; Similar to PID:1177849; identified by sequence similarity; putative. (466 aa)    
Predicted Functional Partners:
VC_0280
Cadaverine/lysine antiporter CadB, putative; Similar to SP:P23891 GB:M67452 GB:M76411 PID:145453 PID:145457; identified by sequence similarity; putative.
  
 
 0.737
VC_0508
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.712
VC_1805
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.703
VC_0433
Arginine/ornithine antiporter; Similar to GB:U00096 PID:1742644 PID:1742655 PID:1787890; identified by sequence similarity; putative.
    
 0.694
VC_A0847
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
 0.694
potE
Putrescine-ornithine antiporter; Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
    
 0.694
rtxA
RTX toxin RtxA; [Multifunctional-autoprocessing repeats-in-toxin]: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm. Upon translocation into the host cell, undergoes autoprocessing in cis mediated by the peptidase C80 domain (also named CPD domain): the protease activity is activated upon binding inositol hexakisphosphate (InsP6) present at the host cell membrane and delivers the Cysteine protease domain-containing toxin F3 chain to the host [...]
 
  
 0.691
VC_0278
Transcriptional activator CadC, putative; Similar to SP:P23890 GB:M67452 PID:145452 PID:536978 GB:U00096; identified by sequence similarity; putative.
  
     0.658
VC_A0253
Antibiotic acetyltransferase; Similar to SP:P26838 GB:M80188 PID:150399; identified by sequence similarity; putative.
  
  
 0.547
VC_A0945
Maltose ABC transporter, periplasmic maltose-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.
 
  
 0.547
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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