Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0274Carbonic anhydrase; Similar to GP:2773324; identified by sequence similarity; putative. (239 aa)    
Predicted Functional Partners:
VC_0586
Carbonic anhydrase, putative; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
     
 0.965
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
 
 0.813
rplE
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.790
VC_A0273
Hypothetical protein; Identified by Glimmer2; putative.
       0.682
VC_0058
Carbonic anhydrase, family 3; Similar to GB:AE000657; identified by sequence similarity; putative.
      
 0.681
VC_0159
RNA-binding protein; Similar to GB:AE000511 PID:2313961; identified by sequence similarity; putative.
  
 
   0.641
tmcA
Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
  
    0.618
VC_1200
Trypsin, putative; Similar to SP:P51588; identified by sequence similarity; putative.
  
 
   0.549
VC_1649
Trypsin, putative; Similar to SP:P26262 PID:200359; identified by sequence similarity; putative.
  
 
   0.549
VC_0795
Citrate/sodium symporter; Similar to GB:M83146 SP:P31602 GB:X12599 GB:Y00525 PID:149181; identified by sequence similarity; putative.
      
 0.530
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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