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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0285Hypothetical protein; Identified by Glimmer2; putative. (223 aa)    
Predicted Functional Partners:
VC_A0284
Hypothetical protein; Identified by Glimmer2; putative.
     
 0.886
VC_A0286
Hypothetical protein; Identified by Glimmer2; putative.
     
 0.870
VC_1548
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.828
rtxA
RTX toxin RtxA; [Multifunctional-autoprocessing repeats-in-toxin]: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm. Upon translocation into the host cell, undergoes autoprocessing in cis mediated by the peptidase C80 domain (also named CPD domain): the protease activity is activated upon binding inositol hexakisphosphate (InsP6) present at the host cell membrane and delivers the Cysteine protease domain-containing toxin F3 chain to the host [...]
  
 
 0.670
VC_A0849
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.616
VC_0414
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.590
VC_1417
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.537
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
       0.415
VC_2232
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.407
VC_0934
Capsular polysaccharide biosynthesis glycosyltransferase, putative; Similar to GB:U00096 SP:P71241 PID:1407618 PID:1736749 PID:1736753; identified by sequence similarity; putative.
   
    0.403
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.