Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0349relB protein; Similar to SP:P07007 GB:X02405 PID:42700 GB:U00096 PID:1742559; identified by sequence similarity; putative. (122 aa)    
Predicted Functional Partners:
VC_A0348
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.914
VC_A0503
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.640
VC_A0359
Plasmid stabilization element ParE, putative; Similar to GB:AL123456; identified by sequence similarity; putative; Belongs to the RelE toxin family.
     
 0.557
VC_A0350
Lipoprotein Blc; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.
     
 0.555
VC_A0489
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.517
higA-1
Antidote protein, putative; Antitoxin component of a type II toxin-antitoxin (TA) system that counteracts the effect of the HigB-1 toxin. Binds to its own promoter and regulates transcription of the higB-1/higA-1 operon.
      
 0.466
higB-1
Killer protein, putative; Toxic component of a type II toxin-antitoxin (TA) system. Inhibits translation by cleavage of mRNA.
      
 0.449
VC_A0477
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
      
 0.442
higA-2
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system that counteracts the effect of the HigB-2 toxin. Binds to its own promoter and regulates transcription of the higB-2/higA-2 operon.
      
 0.425
VC_A0351
Hypothetical protein; Identified by Glimmer2; putative.
       0.419
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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