Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0359Plasmid stabilization element ParE, putative; Similar to GB:AL123456; identified by sequence similarity; putative; Belongs to the RelE toxin family. (99 aa)    
Predicted Functional Partners:
VC_A0360
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
VC_A0311
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.719
VC_A0385
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.719
VC_A0324
DNA-damage-inducible protein J; Similar to PID:984582 GB:U00096 SP:Q47150 PID:1786420; identified by sequence similarity; putative.
   
   0.654
VC_A0477
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
 
   
 0.621
VC_A0361
Hypothetical protein; Identified by Glimmer2; putative.
       0.568
VC_A0349
relB protein; Similar to SP:P07007 GB:X02405 PID:42700 GB:U00096 PID:1742559; identified by sequence similarity; putative.
     
 0.557
VC_A0489
Conserved hypothetical protein; Identified by Glimmer2; putative.
      
 0.522
higA-1
Antidote protein, putative; Antitoxin component of a type II toxin-antitoxin (TA) system that counteracts the effect of the HigB-1 toxin. Binds to its own promoter and regulates transcription of the higB-1/higA-1 operon.
     
 0.496
higB-1
Killer protein, putative; Toxic component of a type II toxin-antitoxin (TA) system. Inhibits translation by cleavage of mRNA.
     
 0.494
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.