STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0447Haemagglutinin associated protein; Similar to GB:X64387 PID:396849 PID:48357; identified by sequence similarity; putative; Belongs to the N(4)/N(6)-methyltransferase family. (230 aa)    
Predicted Functional Partners:
dam
DNA adenine methylase; Methylates DNA within the sequence GATC. Directly involved in methyl-directed DNA mismatch repair; Belongs to the N(4)/N(6)-methyltransferase family.
 
  
 0.699
lon
ATP-dependent protease LA; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
     
 0.665
VC_1576
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0267 family.
 
     0.643
VC_1616
Glutaredoxin, putative; Similar to GB:M60116 SP:P23171 PID:144907; identified by sequence similarity; putative.
  
     0.626
VC_0542
CinA-related protein; Similar to PID:1209307 SP:P51967; identified by sequence similarity; putative; Belongs to the CinA family.
  
 
   0.623
VC_A0198
Site-specific DNA-methyltransferase, putative; Similar to SP:P34906; identified by sequence similarity; putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
  
 0.622
sucD
succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
    0.612
sucC
succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
    0.610
VC_A0446
Haemagglutinin; Similar to GB:X64097 PID:396848 PID:48356; identified by sequence similarity; putative.
       0.561
VC_A0883
Hypothetical protein; Identified by Glimmer2; putative.
     
 0.558
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.