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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
higB-2Hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Inhibits translation by cleavage of mRNA. (110 aa)    
Predicted Functional Partners:
higA-2
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system that counteracts the effect of the HigB-2 toxin. Binds to its own promoter and regulates transcription of the higB-2/higA-2 operon.
 
 
 
 0.998
VC_A0324
DNA-damage-inducible protein J; Similar to PID:984582 GB:U00096 SP:Q47150 PID:1786420; identified by sequence similarity; putative.
 
 
 0.908
VC_A0488
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
 
 
 
 0.745
VC_A0422
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
 
 
 
 0.730
higB-1
Killer protein, putative; Toxic component of a type II toxin-antitoxin (TA) system. Inhibits translation by cleavage of mRNA.
 
   
 0.720
VC_A0312
Hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
   
 
 0.680
VC_A0386
Hypothetical protein; Identified by Glimmer2; putative.
   
 
 0.680
VC_A0445
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
   
 
 0.680
VC_A0477
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
   
 
 0.680
higA-1
Antidote protein, putative; Antitoxin component of a type II toxin-antitoxin (TA) system that counteracts the effect of the HigB-1 toxin. Binds to its own promoter and regulates transcription of the higB-1/higA-1 operon.
 
   
 0.648
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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