STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
higA-2Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system that counteracts the effect of the HigB-2 toxin. Binds to its own promoter and regulates transcription of the higB-2/higA-2 operon. (104 aa)    
Predicted Functional Partners:
higB-2
Hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Inhibits translation by cleavage of mRNA.
 
 
 
 0.998
higA-1
Antidote protein, putative; Antitoxin component of a type II toxin-antitoxin (TA) system that counteracts the effect of the HigB-1 toxin. Binds to its own promoter and regulates transcription of the higB-1/higA-1 operon.
 
   
 0.739
higB-1
Killer protein, putative; Toxic component of a type II toxin-antitoxin (TA) system. Inhibits translation by cleavage of mRNA.
 
   
 0.719
VC_A0198
Site-specific DNA-methyltransferase, putative; Similar to SP:P34906; identified by sequence similarity; putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
  0.600
VC_0139
DPS family protein; Similar to GB:L42023 SP:P45173 PID:1007363 PID:1221482 PID:1205585; identified by sequence similarity; putative; Belongs to the Dps family.
   
    0.566
VC_A0489
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.523
VC_A0467
Hypothetical protein; Identified by Glimmer2; putative.
       0.522
VC_A0470
Acetyltransferase, putative; Similar to GB:U00096 PID:1788774; identified by sequence similarity; putative.
       0.486
VC_A0497
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.461
VC_1872
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
    0.457
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.