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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0485mazG-related protein; Similar to GB:J04039 SP:P33646 PID:416198 PID:882675 GB:U00096; identified by sequence similarity; putative. (123 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.800
VC_A0511
Anaerobic ribonucleoside-triphosphate reductase; Similar to SP:P28903 GB:L06097 GB:U06195 GB:Z46865 PID:146970; identified by sequence similarity; putative.
    
  0.625
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.623
cmk
Cytidylate kinase; Similar to SP:P23863 PID:42839 GB:U00096 PID:1651431 PID:1651438; identified by sequence similarity; putative.
    
  0.620
VC_0585
Hypoxanthine phosphoribosyltransferase; Similar to SP:P18134 GB:X53382 PID:48439; identified by sequence similarity; putative; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
  0.613
VC_1256
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
  0.609
VC_A0486
Hypothetical protein; Identified by Glimmer2; putative.
       0.578
VC_A0487
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.578
VC_0175
Deoxycytidylate deaminase-related protein; Similar to GB:AE000782; identified by sequence similarity; putative.
    
  0.529
VC_A0840
Deoxycytidylate deaminase, putative; Similar to SP:P33968 GB:X70289 PID:396216; identified by sequence similarity; putative.
    
  0.529
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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