Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0513Amino acid biosynthesis aminotransferase; Similar to PID:1806263; identified by sequence similarity; putative. (404 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
   
 0.971
phhA
Phenylalanine-4-hydroxylase; Similar to GB:M88627 SP:P43334 PID:476741; identified by sequence similarity; putative.
  
 
 0.956
VC_1344
4-hydroxyphenylpyruvate dioxygenase; Similar to PID:2108220; identified by sequence similarity; putative.
  
 
 0.955
VC_0705
Chorismate mutase/prephenate dehydratase; Similar to GB:L42023 SP:P43900 PID:1006481 PID:1221267 PID:1205390; identified by sequence similarity; putative.
    
 0.937
VC_0696
Chorismate mutase/prephenate dehydrogenase; Similar to SP:Q02287 GB:M74135 GB:X60420 PID:415010 PID:43345; identified by sequence similarity; putative.
    
 0.936
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.936
VC_1977
Aspartate aminotransferase, putative; Similar to GB:U00096 PID:1788627 PID:1799660; identified by sequence similarity; putative.
   
 0.930
VC_0991
Asparagine synthetase B, glutamine-hydrolyzing; Similar to GB:J05554 SP:P22106 PID:145393 GB:U00096 PID:1651277; identified by sequence similarity; putative.
   
 0.928
hisC
Histidinol-phosphate aminotransferase; Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710; identified by sequence similarity; putative; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
   
 
 0.923
VC_1492
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.922
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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