STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0519Fructose repressor; Similar to SP:P21930 PID:581763; identified by sequence similarity; putative. (326 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
   
 
 0.957
VC_A0518
PTS system, fructose-specific IIA/FPR component; Similar to PID:619247 SP:P24217 GB:U00096 PID:1736835 PID:1788494; identified by sequence similarity; putative.
 
 
 
 0.929
VC_A0517
1-phosphofructokinase; Similar to SP:P23539 GB:X53948 PID:405894 PID:41487 GB:U00096; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family.
 
   
 0.837
VC_2373
Glutamate synthase, large subunit; Similar to GB:X80485 PID:515938 SP:P55037 PID:1652093; identified by sequence similarity; putative.
    
 
 0.764
VC_2376
Glutamate synthase, large subunit; Similar to PID:606151 GB:U00096 PID:1789605; identified by sequence similarity; putative.
    
 
 0.764
VC_A0516
PTS system, fructose-specific IIBC component; Similar to SP:P20966 GB:M23196 PID:405893 PID:450372 GB:U00096; identified by sequence similarity; putative.
 
   
 0.760
sbcD
Exonuclease SbcD, putative; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
       0.746
sbcC
Exonuclease SbcC, putative; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity); Belongs to the SMC family. SbcC subfamily.
       0.746
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
   0.622
vibB
Vibriobactin-specific isochorismatase; Involved in the biosynthesis of the catechol siderophore vibriobactin. Vibriobactin is a chelating compound involved in transporting iron from the bacterial environment into the cell cytoplasm; Belongs to the isochorismatase family.
    
   0.596
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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