Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
clcAConserved hypothetical protein; Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response. (468 aa)    
Predicted Functional Partners:
VC_A0524
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.719
VC_A0530
Pyruvate-flavoredoxin oxidoreductase; Similar to GB:U00096 PID:1742250 PID:1742256 PID:1787642; identified by sequence similarity; putative.
     
 0.599
VC_0784
Sodium/alanine symporter; Similar to GB:AL009126; identified by sequence similarity; putative.
   
  
 0.590
VC_1422
Sodium/alanine symporter; Similar to GB:L42023 SP:P44917 PID:1005967 PID:1220986 PID:1205130; identified by sequence similarity; putative.
   
    0.458
VC_2356
Sodium/alanine symporter; Similar to SP:P30143 GB:U00096 PID:1786188; identified by sequence similarity; putative.
   
    0.458
VC_0191
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.444
VC_1033
Cation transport ATPase, E1-E2 family; Similar to SP:P37617 PID:466605 GB:U00096 PID:1789879; identified by sequence similarity; putative.
     
 0.442
cqsA
Aminotransferase, class II; Required for the synthesis of the quorum-sensing autoinducer CAI-1 ((S)-3-hydroxytridecan-4-one) which probably functions as an intragenus signal; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
     
 0.434
VC_2478
Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
      
 0.425
VC_2479
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
      
 0.425
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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