Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
VC_A0568Hypothetical protein; Identified by Glimmer2; putative. (388 aa)    
Predicted Functional Partners:
VC_A0567
Hypothetical protein; Identified by Glimmer2; putative.
     
 0.830
VC_A0569
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0181 family.
       0.790
VC_1224
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.716
VC_A0565
Sensor histidine kinase; Similar to GB:AE000511 PID:2313251; identified by sequence similarity; putative.
 
     0.700
VC_A0564
NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
       0.685
VC_A0563
NAD(P) transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.
       0.680
VC_A0059
Major outer membrane lipoprotein; Similar to GB:M13176 SP:P09461 GB:M28554 PID:150894 PID:150896; identified by sequence similarity; putative.
  
     0.675
VC_A1047
Mannitol operon repressor; Similar to SP:P36563 PID:434583 PID:466739 GB:U00096 PID:1790029; identified by sequence similarity; putative.
  
     0.672
ompU
Outer membrane protein OmpU; Forms pores that allow passive diffusion of small molecules across the outer membrane.
  
     0.652
VC_A0566
Transcriptional regulator; Similar to SP:Q11156 PID:1449289 PID:2190480 GB:AL123456; identified by sequence similarity; putative.
       0.647
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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