Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0599Hypothetical protein; Identified by Glimmer2; putative. (301 aa)    
Predicted Functional Partners:
VC_A0601
ABC transporter, permease protein; Similar to GB:L42023 PID:1003160 PID:1222041 PID:1204387 PID:1573082; identified by sequence similarity; putative.
 
    0.734
VC_A0600
Repressor protein PhnR, putative; Similar to GP:1763080; identified by sequence similarity; putative.
 
     0.708
VC_1157
Response regulator; Similar to PID:643672; identified by sequence similarity; putative.
  
     0.665
VC_A0602
ABC transporter, ATP-binding protein; Similar to PID:1653298; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
 
     0.597
VC_A0603
ABC transporter, periplasmic substrate-binding protein; Similar to GB:L42023 SP:P43950 SP:P43951 PID:1003162 PID:1003164; identified by sequence similarity; putative.
 
     0.594
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
   0.500
VC_2662
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
   0.494
VC_A1008
Outer membrane protein, putative; Similar to PID:1658032; identified by sequence similarity; putative.
  
     0.470
phnX
Phosphonoacetaldehyde phosphonohydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family.
 
     0.447
ompU
Outer membrane protein OmpU; Forms pores that allow passive diffusion of small molecules across the outer membrane.
  
     0.439
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.