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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0603ABC transporter, periplasmic substrate-binding protein; Similar to GB:L42023 SP:P43950 SP:P43951 PID:1003162 PID:1003164; identified by sequence similarity; putative. (339 aa)    
Predicted Functional Partners:
VC_A0601
ABC transporter, permease protein; Similar to GB:L42023 PID:1003160 PID:1222041 PID:1204387 PID:1573082; identified by sequence similarity; putative.
 
 
 0.959
VC_A0686
iron(III) ABC transporter, permease protein; Similar to PID:1469285 PID:1477454; identified by sequence similarity; putative.
 
 
 0.919
VC_A0602
ABC transporter, ATP-binding protein; Similar to PID:1653298; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
 
 
 0.886
phnX
Phosphonoacetaldehyde phosphonohydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family.
 
   
 0.870
phnW
2-aminoethylphosphonate:pyruvate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
 
  
 0.858
VC_A0851
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
   0.808
VC_0609
iron(III) ABC transporter, permease protein; Similar to PID:1001414 PID:1001407; identified by sequence similarity; putative.
 
 
 0.761
VC_2538
Thiamine ABC transporter, permease protein, putative; Similar to GB:D10483 SP:P31549 PID:216487 GB:U00096 PID:1786254; identified by sequence similarity; putative.
 
 
 0.746
VC_A0605
Aminotransferase, class III; Similar to GB:Pyro_h; identified by sequence similarity; putative; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
     0.670
VC_0610
iron(III) ABC transporter, ATP-binding protein; Similar to PID:1653298; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
  
 
 0.636
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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