STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0605Aminotransferase, class III; Similar to GB:Pyro_h; identified by sequence similarity; putative; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (465 aa)    
Predicted Functional Partners:
phnW
2-aminoethylphosphonate:pyruvate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
 
 0.994
phnX
Phosphonoacetaldehyde phosphonohydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family.
 
  
  0.990
VC_2373
Glutamate synthase, large subunit; Similar to GB:X80485 PID:515938 SP:P55037 PID:1652093; identified by sequence similarity; putative.
      
 0.696
VC_A0603
ABC transporter, periplasmic substrate-binding protein; Similar to GB:L42023 SP:P43950 SP:P43951 PID:1003162 PID:1003164; identified by sequence similarity; putative.
 
     0.677
VC_2033
Alcohol dehydrogenase/acetaldehyde dehydrogenase; Similar to GB:M33504 SP:P17547 GB:X59263 GB:X67326 PID:145206; identified by sequence similarity; putative; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.656
VC_0392
Aminotransferase, class V; Similar to SP:P31030 PID:164759; identified by sequence similarity; putative.
  
 
 0.632
aldA
Aldehyde dehydrogenase; May be involved in V.cholerae virulence, as its expression is under the control of ToxR, a transcriptional activator of several genes associated with virulence.
  
 
 0.583
VC_1745
Succinate-semialdehyde dehydrogenase; Similar to GB:M88334 SP:P25526 PID:147901 GB:U00096 PID:1789015; identified by sequence similarity; putative; Belongs to the aldehyde dehydrogenase family.
  
 
 0.583
VC_1819
Aldehyde dehydrogenase; Similar to GB:M60658 SP:P23240 PID:155276; identified by sequence similarity; putative; Belongs to the aldehyde dehydrogenase family.
  
 
 0.583
astD
Succinylglutamate 5-semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
  
 
 0.583
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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