Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0659Protein F-related protein; Similar to PID:2062640; identified by sequence similarity; putative. (207 aa)    
Predicted Functional Partners:
tolB
tolB protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.837
pal
Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
   
 0.785
VC_A0660
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
VC_2133
Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
  
 
 0.767
VC_2213
Outer membrane protein OmpA; Similar to GP:2641145; identified by sequence similarity; putative; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
 
0.762
VC_A0661
Peptidyl-prolyl cis-trans isomerase-related protein; Similar to GB:U14003 SP:P39311 PID:537048 GB:U00096 PID:1790652; identified by sequence similarity; putative.
     
 0.755
skp
Outer membrane protein OmpH; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm.
  
 
 0.737
VC_1622
Outer membrane protein, putative; Similar to GB:M18975 SP:P13794 GB:M94078 PID:151409 PID:151508; identified by sequence similarity; putative.
  
     0.735
lolA
Outer membrane lipoproteins carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity).
  
 
 0.718
lolB
Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
   
 
 0.701
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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