Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
VC_A0683Sensor protein UhpB; Similar to GB:M89480 SP:P27668 PID:154409; identified by sequence similarity; putative. (527 aa)    
Predicted Functional Partners:
VC_A0682
Transcriptional regulator UhpA; Similar to GB:L10328 SP:P10940 GB:M89479 PID:148112 PID:148117; identified by sequence similarity; putative.
 
 
 
 0.953
VC_1277
Transcriptional regulator, LuxR family; Similar to GB:M21658 SP:P13800 GB:M23649 PID:143089 PID:143499; identified by sequence similarity; putative.
 
 
 
 0.801
VC_1213
Transcriptional regulator, LuxR family; Similar to GB:M24615 SP:P07027 GB:X03691 PID:43289 PID:551848; identified by sequence similarity; putative.
 
 
 
 0.789
VC_A0952
Transcriptional regulator, LuxR family; Similar to PID:1147562 SP:P52106 GB:U00096 PID:1787277; identified by sequence similarity; putative.
 
 
 
 0.773
VC_0396
Transcriptional regulator, LuxR family; Similar to PID:1147562 SP:P52106 GB:U00096 PID:1787277; identified by sequence similarity; putative.
 
 
 
 0.754
VC_2702
Transcriptional regulator, LuxR family; Similar to GB:M60805 SP:P29369 PID:151239; identified by sequence similarity; putative.
 
 
 
 0.749
VC_A0684
Regulatory protein UhpC; Similar to GB:L10328 SP:P09836 GB:M89479 PID:148114 PID:148119; identified by sequence similarity; putative.
  
  
 0.612
VC_A0681
Conserved hypothetical protein; Phosphodiesterase (PDE) that catalyzes the hydrolysis of 3'3'-cyclic GMP-AMP (3'3'-cGAMP), leading to linear 5'-pApG. Also displays 5'-nucleotidase activity, further hydrolyzing 5'-pApG to 5'-ApG. Counteracts the function of the 3'3'-cGAMP synthase DncV, and is involved in the modulation of intracellular 3'3'-cGAMP levels. Enhances bacterial chemotaxis and inhibits intestinal colonization in vivo. Thus exerts a crucial role in regulating bacterial infectivity through catalyzing 3'3'-cGAMP degradation. Is specific for 3'3'-cGAMP since it cannot degrade ot [...]
       0.519
VC_A0685
iron(III) ABC transporter, periplasmic iron-compound-binding protein; Similar to GB:L42023 SP:P43950 SP:P43951 PID:1003162 PID:1003164; identified by sequence similarity; putative.
 
   
 0.472
VC_A0686
iron(III) ABC transporter, permease protein; Similar to PID:1469285 PID:1477454; identified by sequence similarity; putative.
 
     0.409
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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